Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.72 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.44 |
| ▸ | PTAFR | P25105 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EDNRB | P24530 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338366 | 0.84 | BRD4 (1.00) | BRD4BRPF1PTAFRCYP11B2MEN1 | |
| SCHEMBL8313986 | 0.80 | BRD4 (0.48) | BRD4BRPF1CYP11B2 | |
| SCHEMBL11397265 | 0.80 | BRD4 (0.51) | BRD4PTAFREDNRBEDNRAGABRA1 | |
| SCHEMBL23658751 | 0.79 | BRD4 (0.47) | BRD4PTAFRCYP11B2GABRA1GABRA5 | |
| SCHEMBL11401666 | 0.78 | BRD4 (0.50) | BRD4PTAFREDNRBEDNRAGABRA1 | |
| SCHEMBL8316695 | 0.77 | BRD4 (0.46) | BRD4BRPF1HSD17B3MEN1GAA | |
| SCHEMBL13730257 | 0.76 | BRD4 (0.58) | BRD4PTAFRGAAEDNRBEDNRA | |
| SCHEMBL8028802 | 0.75 | BRD4 (0.50) | BRD4PTAFRCYP11B2EDNRBEDNRA | |
| SCHEMBL13730149 | 0.75 | BRD4 (0.57) | BRD4PTAFRGABRA1GABRA5GABRA2 | |
| SCHEMBL13729605 | 0.74 | BRD4 (0.56) | BRD4BRPF1MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112771046-A | Other substituted triazoloquinoxaline derivatives | 格吕伦塔尔有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-112673009-A | Substituted triazoloquinoxaline derivatives | 格吕伦塔尔有限公司 | 2021-04-16 | — | — | CN | disclosed |
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5478823-A | Antiinflammatory agents, antiallergens; tricyclic triazolo derivative | TORAY INDUSTRIES, INC. (JP) | 1995-12-26 | — | — | US | disclosed |
| EP-0617961-A1 | EOSINOPHIL INFILTRATION INHIBITOR | TORAY INDUSTRIES, INC. (JP) | 1994-10-05 | — | — | EP | disclosed |
| EP-0536419-A1 | TRICYCLIC TRIAZOLE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1993-04-14 | — | — | EP | disclosed |