Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316695 | 0.88 | BRD4 (0.46) | BRD4BRPF1 | |
| SCHEMBL11396744 | 0.80 | CYP11B2 (0.38) | BRD4CYP11B2 | |
| SCHEMBL8311751 | 0.80 | BRD4 (0.72) | BRD4BRPF1CYP11B2 | |
| SCHEMBL14996184 | 0.78 | AVPR1A (0.46) | CYP11B2 | |
| SCHEMBL14048243 | 0.72 | CYP11B2 (0.31) | CYP11B2 | |
| SCHEMBL11403505 | 0.70 | BRD4 (0.34) | BRD4CYP11B2 | |
| SCHEMBL11401281 | 0.70 | CA12 (0.36) | BRD4 | |
| SCHEMBL11397293 | 0.69 | CYP11B2 (0.38) | CYP11B2 | |
| SCHEMBL11403511 | 0.68 | GABRA1 (0.39) | CYP11B2 | |
| SCHEMBL11402978 | 0.68 | CYP11B2 (0.40) | CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| EP-0536419-A1 | TRICYCLIC TRIAZOLE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1993-04-14 | — | — | EP | disclosed |