Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14063828 | 0.86 | CAMK2D (0.61) | — | |
| SCHEMBL8311361 | 0.86 | IKBKB (0.56) | — | |
| SCHEMBL14063851 | 0.85 | IKBKB (0.51) | — | |
| SCHEMBL14021219 | 0.82 | PIK3CA (0.58) | — | |
| SCHEMBL14021414 | 0.82 | IKBKB (0.52) | — | |
| SCHEMBL14021251 | 0.82 | JAK2 (0.57) | — | |
| SCHEMBL14021222 | 0.82 | PIK3CA (0.53) | — | |
| SCHEMBL1512786 | 0.81 | PIK3CA (0.55) | SYK | |
| SCHEMBL8312148 | 0.81 | CDK1 (0.62) | — | |
| SCHEMBL3048434 | 0.81 | IKBKB (0.66) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7429599-B2 | Methods for treating or preventing an inflammatory or metabolic condition or inhibiting JNK | SIGNAL PHARMACEUTICALS, LLC (US) | 2008-09-30 | — | — | US | disclosed |
| US-7429599-B2 | Methods for treating or preventing an inflammatory or metabolic condition or inhibiting JNK | SIGNAL PHARMACEUTICALS, LLC (US) | 2008-09-30 | — | — | US | disclosed |
| WO-2004084901-A1 | METHODS FOR TREATING OR PREVENTING AN INFLAMMATORY OR METABOLIC CONDITION BY INHIBITING JNK | SIGNAL PHARMACEUTICALS, LLC (US) | 2004-10-07 | — | — | WO | disclosed |