Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | STAT1 | P42224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8313181 | 0.96 | F2RL3 (0.35) | FFAR4F2RL3CYP19A1MAPTALDH1A1 | |
| SCHEMBL8314511 | 0.88 | FFAR4 (0.39) | FFAR4F2RL3CYP19A1MAPTALDH1A1 | |
| SCHEMBL8311847 | 0.85 | KMT2A (0.39) | F2RL3CYP19A1MAPTALDH1A1MEN1 | |
| SCHEMBL8310220 | 0.85 | KDM4E (0.43) | F2RL3CYP19A1MAPTALDH1A1MEN1 | |
| SCHEMBL8316157 | 0.84 | F2RL3 (0.37) | FFAR4F2RL3CYP19A1MAPTALDH1A1 | |
| SCHEMBL8314218 | 0.84 | CYP19A1 (0.41) | F2RL3CYP19A1MAPTALDH1A1MEN1 | |
| SCHEMBL8314824 | 0.83 | MAPT (0.42) | F2RL3CYP19A1MAPTALDH1A1MEN1 | |
| SCHEMBL8317364 | 0.83 | F2RL3 (0.34) | F2RL3CYP19A1MAPTALDH1A1MEN1 | |
| SCHEMBL8311729 | 0.83 | F2RL3 (0.35) | F2RL3CYP19A1MAPTALDH1A1MEN1 | |
| SCHEMBL8310631 | 0.83 | F2RL3 (0.35) | F2RL3CYP19A1MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5296495-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |