Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2834814 | 0.87 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDTSHRHSD17B10 | |
| SCHEMBL2838027 | 0.86 | KDM4E (0.48) | ALDH1A1KDM4EHPGDTSHRHSD17B10 | |
| SCHEMBL8313939 | 0.85 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDTSHRHSD17B10 | |
| SCHEMBL8306834 | 0.85 | KDM4E (0.55) | ALDH1A1KDM4EHPGDTSHRHSD17B10 | |
| SCHEMBL8315162 | 0.78 | KDM4E (0.51) | ALDH1A1KDM4EHPGDTSHRHSD17B10 | |
| SCHEMBL8313961 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDTSHRHSD17B10 | |
| SCHEMBL2840153 | 0.77 | KMT2A (0.41) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL2834729 | 0.77 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDTSHRHSD17B10 | |
| SCHEMBL2838833 | 0.77 | CA2 (0.39) | ALDH1A1KDM4EHPGDTSHRHSD17B10 | |
| SCHEMBL2834805 | 0.76 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004065391-A1 | 4-AMINOTHIENO[2,3-d]PYRIMIDINE-6-CARBONITRILE DERIVATIVES AS PDE7 INHIBITORS | ALMIRALL PRODESFARMA S.A. (ES) | 2004-08-05 | — | — | WO | disclosed |