Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GUSB | P08236 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28823527 | 0.88 | ALDH1A1 (0.51) | ALDH1A1MAPK1HIF1ACYP1A2CYP3A4 | |
| SCHEMBL29195068 | 0.85 | ALDH1A1 (0.52) | ALDH1A1MAPK1HIF1ACYP1A2CYP3A4 | |
| SCHEMBL11817089 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPK1HIF1ACYP1A2CYP3A4 | |
| SCHEMBL4450405 | 0.83 | ALDH1A1 (0.55) | ALDH1A1MAPK1HIF1ACYP1A2CYP3A4 | |
| SCHEMBL2635851 | 0.82 | ALDH1A1 (0.51) | ALDH1A1MAPK1HIF1ACYP1A2CYP3A4 | |
| SCHEMBL28662918 | 0.81 | HTT (0.47) | ALDH1A1MAPK1HIF1ACYP1A2CYP3A4 | |
| SCHEMBL27847548 | 0.81 | PTGS2 (0.47) | ALDH1A1CYP3A4KMT2AMEN1MAPT | |
| SCHEMBL3807101 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPK1HIF1ACYP1A2CYP3A4 | |
| SCHEMBL8712210 | 0.79 | KMT2A (0.59) | ALDH1A1KMT2AMEN1HPGDLMNA | |
| SCHEMBL12377069 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MAPK1HIF1ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051077-C | Process for preparing benzo[c] phenanthridinium derivatives and compounds prepared by said process | NIPPON KAYAKU KK (JP) | 2000-04-05 | — | — | CN | disclosed |
| EP-0487930-B1 | Benzo[C]phenanthridinium derivatives | NIPPON KAYAKU KK (JP) | 1999-03-24 | — | — | EP | disclosed |
| US-5747502-A | ANTITUMOR AGENTS, ANTIGROWTH AGENTS AND ANTICARCINOGENIC AGENTS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1998-05-05 | — | — | US | disclosed |
| CN-1061964-A | The preparation method of benzo [C] phenanthridines derivative and the new compound for preparing with described method | NIPPON KAYAKU KK (JP) | 1992-06-17 | — | — | CN | disclosed |
| EP-0487930-A1 | Process for preparing benzo[C]phenanthridinium derivatives, and novel compounds prepared by said process | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1992-06-03 | — | — | EP | disclosed |