Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24845046 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KDM4ESMN1; SMN2MAPTKMT2A | |
| SCHEMBL18357113 | 0.75 | TDP1 (0.48) | ALDH1A1 | |
| SCHEMBL923715 | 0.75 | ALDH1A1 (0.50) | ALDH1A1KDM4ECYP2A6ALDH1A3STS | |
| SCHEMBL923714 | 0.75 | ALDH1A1 (0.50) | ALDH1A1KDM4ECYP2A6ALDH1A3STS | |
| SCHEMBL8310894 | 0.75 | HPGD (0.60) | HPGD | |
| SCHEMBL29130069 | 0.74 | ALDH1A1 (0.53) | ALDH1A1KDM4ECYP2A6ALDH1A3STS | |
| SCHEMBL28376659 | 0.74 | ALDH1A1 (0.58) | ALDH1A1KDM4ECYP2A6ALDH1A3STS | |
| SCHEMBL19821133 | 0.72 | BCHE (0.52) | ALDH1A1CYP2A6LMNAMAPTKMT2A | |
| SCHEMBL3466095 | 0.71 | ALDH1A1 (0.60) | ALDH1A1KDM4ECYP2A6SMN1; SMN2LMNA | |
| SCHEMBL8105528 | 0.71 | ALDH1A1 (0.60) | ALDH1A1KDM4ECYP2A6SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597102-B1 | NOVEL BISHETEROCYCLIC DERIVATIVE OR SALT THEREOF AND HYPOGLYCEMIC COMPOSITION | YAMANOUCHI PHARMA CO LTD (JP) | 1999-01-07 | — | — | EP | disclosed |
| US-5508296-A | HYPOGLYCEMIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0597102-A1 | NOVEL BISHETEROCYCLIC DERIVATIVE OR SALT THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1994-05-18 | — | — | EP | disclosed |