Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 10/20 | 0.60 |
| ▸ | PIM1 | P11309 | 5/20 | 0.57 |
| ▸ | PIM2 | Q9P1W9 | 5/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6865620 | 0.75 | HPGD (1.00) | HPGDPIM1PIM2AKR1B1NPC1 | |
| SCHEMBL1299639 | 0.75 | HPGD (1.00) | HPGDPIM1PIM2AKR1B1NPC1 | |
| SCHEMBL1299642 | 0.75 | HPGD (1.00) | HPGDPIM1PIM2AKR1B1NPC1 | |
| SCHEMBL8312155 | 0.75 | ALDH1A1 (0.59) | HPGD | |
| SCHEMBL29029500 | 0.74 | HPGD (0.78) | HPGDPIM1PIM2AKR1B1NPC1 | |
| SCHEMBL29029499 | 0.74 | HPGD (0.78) | HPGDPIM1PIM2AKR1B1NPC1 | |
| SCHEMBL12259371 | 0.74 | PIM1 (0.60) | HPGDPIM1PIM2AKR1B1NPC1 | |
| SCHEMBL9212605 | 0.73 | PIM1 (0.74) | HPGDPIM1PIM2MAOAMAOB | |
| SCHEMBL9212601 | 0.73 | PIM1 (0.74) | HPGDPIM1PIM2MAOAMAOB | |
| SCHEMBL1247705 | 0.73 | PIM1 (1.00) | HPGDPIM1PIM2AKR1B1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597102-B1 | NOVEL BISHETEROCYCLIC DERIVATIVE OR SALT THEREOF AND HYPOGLYCEMIC COMPOSITION | YAMANOUCHI PHARMA CO LTD (JP) | 1999-01-07 | — | — | EP | disclosed |
| US-5508296-A | HYPOGLYCEMIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0597102-A1 | NOVEL BISHETEROCYCLIC DERIVATIVE OR SALT THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1994-05-18 | — | — | EP | disclosed |