Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.42 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312015 | 0.83 | APP (0.46) | APPF2RL3KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL8316374 | 0.77 | MAPT (0.49) | KDM4ERAB9ASMN1; SMN2ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8312117 | 0.77 | RAB9A (0.42) | KDM4ERAB9ASMN1; SMN2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL8315810 | 0.76 | CYP1A1 (0.45) | KDM4ERAB9ASMN1; SMN2ATMALDH1A1 | |
| SCHEMBL8315597 | 0.76 | APP (0.41) | APPF2RL3KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL8314147 | 0.75 | F2RL3 (0.31) | F2RL3 | |
| Hydrochloric Acid SCHEMBL8314842 | 0.70 | KDM4E (0.44) | KDM4EALDH1A1HPGDGAAMAOB | |
| SCHEMBL8317000 | 0.70 | CYP1A1 (0.44) | KDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL8316999 | 0.70 | CYP1A1 (0.44) | KDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL8317005 | 0.69 | KDM4E (0.42) | KDM4ERAB9ASMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5296495-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |