Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312254 | 0.83 | APP (0.42) | APPSMN1; SMN2MAPTRAB9AALDH1A1 | |
| SCHEMBL8311101 | 0.81 | KDM4E (0.48) | APPSMN1; SMN2MAPTRAB9AALDH1A1 | |
| SCHEMBL8311014 | 0.78 | MAPT (0.42) | SMN1; SMN2MAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL8315007 | 0.76 | NPC1 (0.40) | SMN1; SMN2MAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL8309970 | 0.72 | KDM4E (0.37) | SMN1; SMN2MAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL8314504 | 0.70 | RAB9A (0.70) | APPSMN1; SMN2MAPTRAB9AALDH1A1 | |
| SCHEMBL14095472 | 0.70 | ACHE (0.42) | SMN1; SMN2MAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL8310770 | 0.69 | APP (0.47) | APPSMN1; SMN2MAPTRAB9AALDH1A1 | |
| SCHEMBL8317400 | 0.69 | MAPT (0.46) | APPSMN1; SMN2MAPTRAB9AALDH1A1 | |
| SCHEMBL8167973 | 0.68 | ACHE (0.49) | SMN1; SMN2MAPTRAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5296495-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |