Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | CASK | O14936 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6369876 | 0.84 | HPGDS (0.45) | CD38 | |
| SCHEMBL6364295 | 0.81 | AURKA (0.44) | CD38 | |
| SCHEMBL6368598 | 0.80 | IRAK4 (0.48) | EGFR | |
| SCHEMBL6363927 | 0.78 | AURKA (0.49) | — | |
| SCHEMBL6369862 | 0.76 | KDR (0.48) | EGFREHMT1 | |
| SCHEMBL6368444 | 0.75 | IRAK4 (0.45) | CD38EGFR | |
| SCHEMBL6363667 | 0.74 | CD38 (0.41) | CD38EGFR | |
| SCHEMBL6363672 | 0.74 | CD38 (0.41) | CD38EGFR | |
| SCHEMBL16332916 | 0.70 | POLB (0.47) | — | |
| SCHEMBL6368103 | 0.69 | IRAK4 (0.45) | CD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016925-A1 | AZAQUINAZOLINE DERIVATIVES | PFIZER LIMITED (GB) | 2005-02-24 | — | — | WO | disclosed |