Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 16/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310904 | 1.00 | SIGMAR1 (0.46) | SIGMAR1ITGB3ITGA2BGRM2F10 | |
| SCHEMBL8316462 | 1.00 | SIGMAR1 (0.46) | SIGMAR1ITGB3ITGA2BGRM2F10 | |
| SCHEMBL8311141 | 0.89 | SIGMAR1 (0.44) | SIGMAR1ITGB3ITGA2BF10 | |
| SCHEMBL8314784 | 0.89 | SIGMAR1 (0.44) | SIGMAR1ITGB3ITGA2BF10 | |
| SCHEMBL8311319 | 0.89 | SIGMAR1 (0.42) | SIGMAR1ITGB3ITGA2BGRM2F10 | |
| SCHEMBL8948664 | 0.88 | SIGMAR1 (0.45) | SIGMAR1ITGB3ITGA2BGRM2F10 | |
| SCHEMBL8310860 | 0.87 | ITGB3 (0.50) | SIGMAR1ITGB3ITGA2BF10 | |
| SCHEMBL8313647 | 0.87 | SIGMAR1 (0.46) | SIGMAR1ITGB3ITGA2BGRM2 | |
| SCHEMBL8314726 | 0.86 | SIGMAR1 (0.44) | SIGMAR1ITGB3ITGA2B | |
| SCHEMBL8948621 | 0.86 | F10 (0.52) | SIGMAR1ITGB3ITGA2BGRM2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623615-B1 | Substituted 1-phenyl-oxazolidin-2-one derivatives, their preparation and their use as adhesion-receptor antagonists | MERCK PATENT GMBH (DE) | 1999-06-30 | — | — | EP | disclosed |
| EP-0623615-A1 | Adhesion-receptor antagonists | MERCK PATENT GmbH (DE) | 1994-11-09 | — | — | EP | disclosed |