Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16566170 | 0.91 | ALDH1A1 (0.50) | ALDH1A1MAPTHSP90AA1HTTGAA | |
| SCHEMBL14821834 | 0.84 | ALDH1A1 (0.61) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL16450893 | 0.82 | HSP90AA1 (0.59) | ALDH1A1MAPTHSP90AA1MEN1KMT2A | |
| SCHEMBL12235539 | 0.82 | HSP90AA1 (0.59) | ALDH1A1MAPTHSP90AA1MEN1KMT2A | |
| SCHEMBL13478303 | 0.82 | L3MBTL1 (0.47) | ALDH1A1MAPTHSP90AA1HTTGAA | |
| SCHEMBL13057567 | 0.82 | ALDH1A1 (0.51) | ALDH1A1MAPTHSP90AA1KMT2AGAA | |
| SCHEMBL3485977 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPTGAAKDM4EPOLB | |
| SCHEMBL774049 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPTGAAKDM4EPOLB | |
| SCHEMBL8884265 | 0.81 | L3MBTL1 (0.64) | ALDH1A1MAPTHSP90AA1HTTMEN1 | |
| SCHEMBL18466208 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPTHSP90AA1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063213-A2 | PEPTIDES WHICH TARGET TUMOR AND ENDOTHELIAL CELLS, COMPOSITIONS AND USES THEREOF | ATTENUON, LLC (US) | 2004-07-29 | — | — | WO | disclosed |