Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | OXTR | P30559 | 1/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414169 | 0.90 | AVPR2 (0.45) | AVPR2KMT2AMEN1AVPR1A | |
| SCHEMBL8318866 | 0.89 | KCNJ5 (0.47) | AVPR2 | |
| SCHEMBL7332706 | 0.87 | AVPR2 (0.47) | AVPR2KMT2AMEN1AVPR1A | |
| SCHEMBL8315540 | 0.86 | HSD11B1 (0.48) | KMT2AMEN1 | |
| SCHEMBL8315401 | 0.83 | AVPR1A (0.51) | AVPR2OXTRAVPR1A | |
| SCHEMBL8315722 | 0.83 | AVPR1A (0.64) | AVPR2OXTRAVPR1A | |
| SCHEMBL8315058 | 0.82 | KMT2A (0.43) | AVPR2KMT2AMEN1OXTRAVPR1A | |
| SCHEMBL8313980 | 0.82 | AVPR1A (0.52) | AVPR2OXTRAVPR1A | |
| SCHEMBL8314000 | 0.81 | AVPR1A (0.56) | AVPR2OXTRAVPR1A | |
| SCHEMBL8557382 | 0.80 | AVPR2 (0.50) | AVPR2KMT2AMEN1OXTRAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |