Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416297 | 0.89 | HSD11B1 (0.47) | HSD11B1KDM4EALDH1A1MAPTNR4A1 | |
| SCHEMBL8312803 | 0.86 | AVPR2 (0.49) | KMT2AMEN1 | |
| SCHEMBL8318866 | 0.86 | KCNJ5 (0.47) | NAMPTKCNQ2 | |
| SCHEMBL7332706 | 0.83 | AVPR2 (0.47) | KMT2ANAMPTMEN1 | |
| SCHEMBL8558667 | 0.79 | NAMPT (0.54) | HSD11B1KDM4EALDH1A1MAPTNR4A1 | |
| SCHEMBL8315722 | 0.78 | AVPR1A (0.64) | — | |
| SCHEMBL8314568 | 0.78 | AVPR1A (0.58) | HSD11B1 | |
| SCHEMBL8314325 | 0.78 | AVPR1A (0.52) | KMT2AMEN1 | |
| SCHEMBL8315401 | 0.78 | AVPR1A (0.51) | — | |
| SCHEMBL7349542 | 0.78 | AVPR1A (0.65) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |