Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 13/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7686889 | 0.99 | EGLN1 (0.71) | EGLN1L3MBTL1ALDH1A1P2RX1NPC1 | |
| SCHEMBL7964145 | 0.85 | EGLN1 (0.73) | EGLN1ALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL7687778 | 0.85 | EGLN1 (0.73) | EGLN1ALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL7953380 | 0.85 | EGLN1 (0.73) | EGLN1L3MBTL1ALDH1A1P2RX1MEN1 | |
| SCHEMBL8309229 | 0.85 | EGLN1 (0.73) | EGLN1L3MBTL1ALDH1A1NPC1MEN1 | |
| Hydrochloric Acid SCHEMBL7692185 | 0.85 | EGLN1 (0.76) | EGLN1L3MBTL1ALDH1A1NPC1MEN1 | |
| SCHEMBL2201326 | 0.84 | EGLN1 (1.00) | EGLN1ALDH1A1NPC1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7691042 | 0.84 | EGLN1 (0.71) | EGLN1L3MBTL1ALDH1A1NPC1MEN1 | |
| Hydrochloric Acid SCHEMBL7690499 | 0.84 | EGLN1 (0.71) | EGLN1ALDH1A1NPC1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7690422 | 0.84 | EGLN1 (0.71) | EGLN1L3MBTL1ALDH1A1P2RX1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927164-A1 | 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998011073-A1 | 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1998-03-19 | — | — | WO | disclosed |