Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 13/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CD74 | P04233 | 1/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | CBR1 | P16152 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7691042 | 0.99 | EGLN1 (0.71) | EGLN1ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL19347367 | 0.90 | EGLN1 (0.72) | EGLN1ALDH1A1KDR | |
| Hydrochloric Acid SCHEMBL7685037 | 0.89 | EGLN1 (0.70) | EGLN1ALDH1A1NPC1KDR | |
| SCHEMBL7953380 | 0.85 | EGLN1 (0.73) | EGLN1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL8312850 | 0.85 | EGLN1 (0.73) | EGLN1ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL7964145 | 0.85 | EGLN1 (0.73) | EGLN1ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL7687778 | 0.85 | EGLN1 (0.73) | EGLN1ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL7686886 | 0.85 | EGLN1 (0.77) | EGLN1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL2201326 | 0.84 | EGLN1 (1.00) | EGLN1ALDH1A1MEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL7690422 | 0.84 | EGLN1 (0.71) | EGLN1ALDH1A1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927164-A1 | 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998011073-A1 | 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1998-03-19 | — | — | WO | disclosed |