Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2171686 | 0.80 | LCK (0.43) | LCKRAB9ANPC1SMN1; SMN2PKM | |
| SCHEMBL5777843 | 0.80 | PLAU (0.46) | NCEH1PLAULCKMRGPRX4CYP11B1 | |
| SCHEMBL30897207 | 0.80 | LCK (0.43) | LCKRAB9ANPC1SMN1; SMN2PKM | |
| SCHEMBL5776609 | 0.80 | PLAU (0.46) | NCEH1PLAULCKRAB9ANPC1 | |
| SCHEMBL5775744 | 0.80 | NCEH1 (0.47) | NCEH1PLAULCKMRGPRX4CYP11B1 | |
| SCHEMBL29089553 | 0.80 | KMT2A (0.48) | LCKRAB9ANPC1SMN1; SMN2PKM | |
| SCHEMBL15012676 | 0.78 | HTT (0.48) | NCEH1LCKRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7345962 | 0.77 | PLAU (0.46) | NCEH1PLAULCKMRGPRX4CYP11B1 | |
| SCHEMBL5566033 | 0.76 | PLAU (0.64) | PLAULCKRAB9ANPC1MRGPRX4 | |
| SCHEMBL23619741 | 0.76 | TRPV4 (0.43) | NCEH1PLAULCKSMN1; SMN2MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217794-B2 | Compounds and methods for treatment of thrombosis | DAIAMED, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| US-7217794-B2 | Compounds and methods for treatment of thrombosis | DAIAMED, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| WO-2004089297-A2 | COMPOUNDS AND METHODS FOR TREATMENT OF THROMBOSIS | SUNTORY PHARMACEUTICAL RESEARCH LABORATORIES, LLC (US) | 2004-10-21 | — | — | WO | disclosed |