Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 4/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.40 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7386444 | 0.90 | PLAU (0.41) | PLAUPOLBRXFP1NCEH1EGLN2 | |
| SCHEMBL5776609 | 0.80 | PLAU (0.46) | PLAUNAMPTLCKPOLBRXFP1 | |
| SCHEMBL5775744 | 0.80 | NCEH1 (0.47) | PLAUNAMPTLCKPOLBRXFP1 | |
| SCHEMBL5777843 | 0.80 | PLAU (0.46) | PLAUNAMPTLCKPOLBRXFP1 | |
| SCHEMBL8312949 | 0.77 | NCEH1 (0.44) | PLAUNAMPTLCKPOLBRXFP1 | |
| SCHEMBL5566033 | 0.76 | PLAU (0.64) | PLAUNAMPTLCKPOLBRXFP1 | |
| SCHEMBL23619741 | 0.76 | TRPV4 (0.43) | PLAUNAMPTLCKPOLBRXFP1 | |
| SCHEMBL5566965 | 0.76 | VCAM1 (0.45) | PLAULCKPOLBRXFP1NCEH1 | |
| SCHEMBL30812891 | 0.76 | TRPV4 (0.43) | PLAUNAMPTLCKPOLBRXFP1 | |
| SCHEMBL3558563 | 0.75 | PLAU (0.59) | PLAUNAMPTLCKPOLBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284796-B1 | NAPHTHAMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-09-04 | — | — | US | disclosed |