Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.30 |
| ▸ | IL5 | P05113 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17813556 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HPGDCYP11B2GPR55 | |
| SCHEMBL19039381 | 0.73 | UHRF1 (0.39) | IL5 | |
| SCHEMBL8344117 | 0.72 | MAPT (0.45) | ALDH1A1HPGD | |
| SCHEMBL8343898 | 0.70 | KAT2B (0.35) | ALDH1A1HPGD | |
| SCHEMBL8344120 | 0.70 | PIK3CD (0.33) | ALDH1A1HPGD | |
| SCHEMBL8311223 | 0.67 | ADORA2B (0.49) | ALDH1A1HPGD | |
| SCHEMBL171826 | 0.66 | KDM4E (0.48) | ALDH1A1HPGD | |
| SCHEMBL46341 | 0.66 | ALDH1A1 (0.35) | ALDH1A1HPGD | |
| SCHEMBL17813544 | 0.66 | PIK3CD (0.34) | ALDH1A1HPGDGPR55 | |
| SCHEMBL8343894 | 0.64 | CCR1 (0.38) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004064842-A1 | AMIDE AND ESTER MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-08-05 | — | — | WO | disclosed |
| WO-2004014384-A2 | CYCLIC COMPOUNDS CONTAINING ZINC BINDING GROUPS AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |