Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 5/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.64 |
| ▸ | PTAFR | P25105 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583543 | 0.88 | OPRD1 (0.62) | OPRD1KCNH2PTAFRKMT2AMEN1 | |
| SCHEMBL12751010 | 0.83 | OPRD1 (0.48) | OPRD1KCNH2KMT2ALMNAOPRM1 | |
| SCHEMBL2457390 | 0.80 | OPRD1 (0.61) | OPRD1KCNH2LMNAOPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL7647391 | 0.79 | OPRD1 (0.59) | OPRD1KCNH2LMNAOPRM1OPRK1 | |
| Bromide SCHEMBL10598951 | 0.79 | OPRD1 (0.59) | OPRD1KCNH2LMNAOPRM1OPRK1 | |
| SCHEMBL30567989 | 0.79 | OPRD1 (0.56) | OPRD1KCNH2PTAFRKMT2AMEN1 | |
| SCHEMBL21381637 | 0.79 | OPRD1 (0.56) | OPRD1KCNH2PTAFRKMT2AMEN1 | |
| SCHEMBL22491502 | 0.77 | OPRD1 (0.43) | OPRD1KCNH2LMNAOPRM1OPRK1 | |
| SCHEMBL13272027 | 0.75 | PTAFR (0.64) | OPRD1KCNH2PTAFRKMT2AMEN1 | |
| 2-Picolinic Acid SCHEMBL25335049 | 0.74 | L3MBTL1 (0.77) | OPRD1KCNH2KMT2ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0536419-A1 | TRICYCLIC TRIAZOLE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1993-04-14 | — | — | EP | disclosed |