Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | MMP13 | P45452 | 7/20 | 0.47 |
| ▸ | MMP12 | P39900 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 5/20 | 0.47 |
| ▸ | MMP9 | P14780 | 5/20 | 0.47 |
| ▸ | MMP1 | P03956 | 3/20 | 0.47 |
| ▸ | MMP3 | P08254 | 3/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6270534 | 1.00 | CTSK (0.49) | CTSKMMP13MMP12MMP8MMP2 | |
| SCHEMBL6270538 | 1.00 | CTSK (0.49) | CTSKMMP13MMP12MMP8MMP2 | |
| SCHEMBL6269979 | 1.00 | CTSK (0.49) | CTSKMMP13MMP12MMP8MMP2 | |
| SCHEMBL8314491 | 0.94 | CTSK (0.54) | CTSKMMP13MMP12MMP8MMP2 | |
| SCHEMBL6271166 | 0.94 | CTSK (0.54) | CTSKMMP13MMP12MMP8MMP2 | |
| SCHEMBL6271164 | 0.94 | CTSK (0.54) | CTSKMMP13MMP12MMP8MMP2 | |
| SCHEMBL6270676 | 0.87 | MMP13 (0.53) | CTSKMMP13MMP12MMP2MMP9 | |
| SCHEMBL6807393 | 0.87 | MMP13 (0.53) | CTSKMMP13MMP12MMP2MMP9 | |
| SCHEMBL6270678 | 0.87 | MMP13 (0.53) | CTSKMMP13MMP12MMP2MMP9 | |
| SCHEMBL6266968 | 0.84 | MMP13 (0.44) | MMP13MMP12MMP8MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073599-A2 | INHIBITORS OF HEPATITIS C VIRUS, COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2004-09-02 | — | — | WO | disclosed |