Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 13/20 | 0.69 |
| ▸ | AVPR1A | P37288 | 13/20 | 0.69 |
| ▸ | OXTR | P30559 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334076 | 0.85 | AVPR2 (0.68) | AVPR2AVPR1AOXTR | |
| SCHEMBL8316487 | 0.84 | AVPR1A (0.49) | AVPR2AVPR1AOXTR | |
| SCHEMBL7333870 | 0.83 | AVPR2 (0.64) | AVPR2AVPR1AOXTR | |
| SCHEMBL7341288 | 0.82 | AVPR2 (0.68) | AVPR2AVPR1AOXTR | |
| SCHEMBL8313051 | 0.81 | AVPR2 (1.00) | AVPR2AVPR1AOXTR | |
| SCHEMBL8318107 | 0.76 | AVPR2 (0.65) | AVPR2AVPR1A | |
| SCHEMBL8314568 | 0.75 | AVPR1A (0.58) | AVPR2AVPR1A | |
| SCHEMBL8315247 | 0.74 | NPSR1 (0.44) | AVPR2AVPR1ALMNATP53 | |
| SCHEMBL8318709 | 0.74 | AVPR2 (0.54) | AVPR2AVPR1A | |
| SCHEMBL8314641 | 0.74 | AVPR2 (0.88) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |