Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317245 | 0.87 | AVPR2 (0.46) | RAB9AALDH1A1AVPR2AVPR1A | |
| SCHEMBL8314568 | 0.83 | AVPR1A (0.58) | AVPR2AVPR1A | |
| SCHEMBL7333870 | 0.80 | AVPR2 (0.64) | RAB9AALDH1A1AVPR2AVPR1A | |
| SCHEMBL7337562 | 0.79 | AVPR2 (0.44) | RAB9AAVPR2LMNA | |
| SCHEMBL8317063 | 0.78 | AVPR2 (0.67) | AVPR2AVPR1A | |
| SCHEMBL8318107 | 0.78 | AVPR2 (0.65) | AVPR2AVPR1A | |
| SCHEMBL8318709 | 0.76 | AVPR2 (0.54) | RAB9AAVPR2AVPR1A | |
| SCHEMBL8312759 | 0.76 | AVPR1A (0.55) | AVPR2AVPR1A | |
| SCHEMBL7334076 | 0.76 | AVPR2 (0.68) | RAB9AAVPR2AVPR1A | |
| SCHEMBL8316487 | 0.75 | AVPR1A (0.49) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |