Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 11/20 | 0.49 |
| ▸ | AVPR2 | P30518 | 11/20 | 0.49 |
| ▸ | PNLIP | P16233 | 1/20 | 0.49 |
| ▸ | OXTR | P30559 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.44 |
| ▸ | F2R | P25116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316224 | 0.87 | AVPR2 (0.44) | AVPR1AAVPR2OXTRRXFP1 | |
| SCHEMBL8313809 | 0.84 | AVPR2 (0.69) | AVPR1AAVPR2OXTR | |
| SCHEMBL7333870 | 0.84 | AVPR2 (0.64) | AVPR1AAVPR2OXTR | |
| SCHEMBL7334076 | 0.82 | AVPR2 (0.68) | AVPR1AAVPR2OXTR | |
| SCHEMBL7341288 | 0.82 | AVPR2 (0.68) | AVPR1AAVPR2OXTR | |
| SCHEMBL7415555 | 0.78 | AVPR2 (0.49) | AVPR1AAVPR2 | |
| SCHEMBL6989072 | 0.77 | AVPR1A (0.55) | AVPR1AAVPR2PNLIPKCNK3KCNK9 | |
| SCHEMBL8318107 | 0.76 | AVPR2 (0.65) | AVPR1AAVPR2 | |
| SCHEMBL8314568 | 0.76 | AVPR1A (0.58) | AVPR1AAVPR2 | |
| SCHEMBL8317555 | 0.75 | AVPR2 (0.54) | AVPR1AAVPR2OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |