Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALPL | P05186 | 3/20 | 0.36 |
| ▸ | ALPG | P10696 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | ALPI | P09923 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314617 | 0.87 | LMNA (0.37) | GAAMAPTMEN1KMT2APOLB | |
| SCHEMBL8315357 | 0.78 | GAA (0.42) | GAATSHRCA12CA9CA2 | |
| SCHEMBL13158679 | 0.72 | CA12 (0.41) | GAATSHRCA12CA9CA2 | |
| SCHEMBL8317764 | 0.69 | CA12 (0.38) | GAATSHRCA12CA9CA2 | |
| SCHEMBL8316610 | 0.68 | OPRL1 (0.42) | GAACA12CA9CA2L3MBTL1 | |
| SCHEMBL8315782 | 0.65 | CA12 (0.35) | GAACA12CA9CA2PRCP | |
| SCHEMBL8314203 | 0.65 | HTT (0.38) | GAATSHRMAPTMEN1KMT2A | |
| SCHEMBL25502419 | 0.64 | GAA (0.58) | GAATSHRMAPTMEN1KMT2A | |
| SCHEMBL10532082 | 0.64 | PRCP (0.39) | GAATSHRMAPTMEN1KMT2A | |
| SCHEMBL29851768 | 0.64 | PRCP (0.39) | GAATSHRMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929072-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY LIMITED (GB) | 1999-07-27 | — | — | US | disclosed |
| EP-0897921-A1 | Benzothiadiazinyl-indole derivatives and their use as serotonin receptor ligands | ELI LILLY AND COMPANY LIMITED (GB) | 1999-02-24 | — | — | EP | disclosed |