Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312883 | 0.78 | DRD2 (0.34) | — | |
| SCHEMBL12949141 | 0.78 | CHRM3 (0.37) | CHRM3 | |
| SCHEMBL12928650 | 0.76 | CHRM3 (0.36) | CHRM3 | |
| SCHEMBL8309553 | 0.76 | CHRM3 (0.36) | CHRM3 | |
| SCHEMBL12083995 | 0.73 | ALDH1A1 (0.44) | CHRM3 | |
| SCHEMBL11382530 | 0.73 | CYP1A2 (0.35) | — | |
| SCHEMBL12465180 | 0.72 | — | — | |
| SCHEMBL7541983 | 0.70 | KMT2A (0.36) | CHRM3 | |
| SCHEMBL8341325 | 0.69 | TSHR (0.40) | — | |
| SCHEMBL13606807 | 0.67 | ESR2 (0.40) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581532-B1 | PYRAZOLO¬3,4-B PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LTD (GB) | 2010-04-28 | — | — | EP | disclosed |
| WO-2004056823-A1 | PYRAZOLO[3,4-b]PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |
| WO-2004024728-A2 | PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-03-25 | — | — | WO | disclosed |