Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316328 | 0.87 | TLR8 (0.49) | APOBEC3GMAPTKMT2ARAB9AMEN1 | |
| SCHEMBL8314180 | 0.86 | APOBEC3G (0.41) | APOBEC3GMAPTKMT2ARAB9AMEN1 | |
| SCHEMBL8451109 | 0.83 | CNR2 (0.49) | KMT2AMEN1CDK9DYRK1ADYRK2 | |
| SCHEMBL24549317 | 0.82 | DCTPP1 (0.44) | APOBEC3GMAPTKMT2ACDK9DYRK1A | |
| SCHEMBL8314046 | 0.82 | LMNA (0.56) | MAPTKMT2ARAB9ANPC1TP53 | |
| SCHEMBL740756 | 0.74 | HRH1 (0.52) | MAPTTP53SMN1; SMN2MCHR1OPRM1 | |
| SCHEMBL740755 | 0.74 | HRH1 (0.52) | MAPTTP53SMN1; SMN2MCHR1OPRM1 | |
| SCHEMBL24549185 | 0.73 | CNR2 (0.46) | KMT2ARAB9AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL24549319 | 0.72 | IDO1 (0.52) | MAPTKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL739667 | 0.71 | KCNH2 (0.43) | MAPTTP53SMN1; SMN2USP2GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0536419-A1 | TRICYCLIC TRIAZOLE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1993-04-14 | — | — | EP | disclosed |