Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 11/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 10/20 | 0.40 |
| ▸ | TUBB | P07437 | 10/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 10/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 10/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 10/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 10/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 10/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 10/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 10/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314245 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1GAAMAPTHTT | |
| Hydrochloric Acid SCHEMBL8459129 | 0.99 | KDM4E (0.44) | KDM4EALDH1A1GAAMAPTHTT | |
| Hydrochloric Acid SCHEMBL8459126 | 0.99 | KDM4E (0.44) | KDM4EALDH1A1GAAMAPTHTT | |
| SCHEMBL9694219 | 0.87 | ALDH1A1 (0.45) | ALDH1A1MAPTHPGDTUBB1TUBB4A | |
| SCHEMBL9694216 | 0.87 | ALDH1A1 (0.45) | ALDH1A1MAPTHPGDTUBB1TUBB4A | |
| Hydrochloric Acid SCHEMBL8316467 | 0.86 | ALDH1A1 (0.44) | KDM4EALDH1A1MAPTHPGDTUBB1 | |
| Hydrochloric Acid SCHEMBL8316464 | 0.86 | ALDH1A1 (0.44) | KDM4EALDH1A1MAPTHPGDTUBB1 | |
| SCHEMBL8315265 | 0.86 | PARP1 (0.46) | KDM4EGAAMAPTMAPK1TUBB1 | |
| SCHEMBL8315262 | 0.86 | PARP1 (0.46) | KDM4EGAAMAPTMAPK1TUBB1 | |
| SCHEMBL8316322 | 0.84 | APP (0.46) | ALDH1A1GAAMAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351856-B1 | Thiazolo[5,4-b]azepine compounds | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-09-15 | — | — | EP | claimed |
| US-4956360-A | LIPOPEROXIDE INHIBITORS, ENZYME INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-09-11 | — | — | US | claimed |