SCHEMBL831430

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29674921	1.00	HDAC6 (0.51)	HDAC6HDAC1MAPTTOP2AMEN1
	SCHEMBL831429	1.00	HDAC6 (0.51)	HDAC6HDAC1MAPTTOP2AMEN1
	SCHEMBL834052	0.89	ALDH1A1 (0.57)	MAPTTOP2AMEN1CYP2C19KMT2A
	SCHEMBL22410559	0.89	HDAC6 (0.53)	HDAC6HDAC1MAPTALDH1A1MAPK1
	SCHEMBL834053	0.89	ALDH1A1 (0.57)	MAPTTOP2AMEN1CYP2C19KMT2A
	SCHEMBL833458	0.86	MAPT (0.43)	MAPTMEN1CYP2C19KMT2AALDH1A1
	SCHEMBL833459	0.86	MAPT (0.43)	MAPTMEN1CYP2C19KMT2AALDH1A1
	SCHEMBL833038	0.85	ALDH1A1 (0.50)	MAPTMEN1CYP2C19KMT2AALDH1A1
	SCHEMBL833039	0.85	ALDH1A1 (0.50)	MAPTMEN1CYP2C19KMT2AALDH1A1
	SCHEMBL832010	0.85	MAPT (0.46)	MAPTMEN1CYP2C19KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.