Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 12/20 | 0.55 |
| ▸ | MEN1 | O00255 | 11/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.55 |
| ▸ | NPC1 | O15118 | 7/20 | 0.55 |
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.55 |
| ▸ | RELA | Q04206 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312888 | 0.83 | MAPT (0.56) | MAPTMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL8314667 | 0.82 | MEN1 (0.52) | MAPTMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL8310447 | 0.81 | CYP19A1 (0.50) | MAPTMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL8310727 | 0.80 | MAPT (0.44) | MAOBMAPTMEN1KMT2AKDM4E | |
| SCHEMBL8314504 | 0.79 | RAB9A (0.70) | MAOBMAPTKDM4ENPC1RAB9A | |
| SCHEMBL8314824 | 0.77 | MAPT (0.42) | MAOBMAPTMEN1KMT2AKDM4E | |
| SCHEMBL8310999 | 0.76 | KDM4E (0.50) | MAOBMAPTKMT2AKDM4ENPC1 | |
| SCHEMBL8696641 | 0.75 | F2RL3 (0.53) | MAPTKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8310435 | 0.75 | KDM4E (0.49) | MAOBMAPTMEN1KMT2AKDM4E | |
| SCHEMBL8317400 | 0.74 | MAPT (0.46) | MAOBMAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5296495-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |