Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 14/20 | 1.00 |
| ▸ | DRD3 | P35462 | 13/20 | 1.00 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR5A | P47898 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315986 | 1.00 | DRD2 (1.00) | DRD2DRD3SIGMAR1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL8686327 | 0.99 | DRD2 (0.98) | DRD2DRD3SIGMAR1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL8686468 | 0.99 | DRD2 (0.98) | DRD2DRD3SIGMAR1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL8903625 | 0.99 | DRD2 (0.98) | DRD2DRD3SIGMAR1MAPTMAPK1 | |
| SCHEMBL8317822 | 0.91 | DRD2 (1.00) | DRD2DRD3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8903800 | 0.90 | DRD2 (0.98) | DRD2DRD3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8686317 | 0.90 | DRD2 (0.98) | DRD2DRD3SIGMAR1 | |
| SCHEMBL8386483 | 0.83 | DRD2 (0.71) | DRD2DRD3MAPTMAPK1TDP1 | |
| SCHEMBL8318539 | 0.83 | DRD2 (0.81) | DRD2DRD3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8685262 | 0.82 | DRD2 (0.80) | DRD2DRD3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691342-B1 | Benzopyran derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-04-28 | — | — | EP | disclosed |
| EP-0691342-A1 | Benzopyrane derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-01-10 | — | — | EP | disclosed |