Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315056 | 0.94 | TLR8 (0.45) | TLR8MCHR1IRAK4ALDH1A1HPGD | |
| SCHEMBL19612294 | 0.80 | CYP1A2 (0.46) | TLR8MCHR1IRAK4ALDH1A1HPGD | |
| SCHEMBL426014 | 0.79 | ALDH1A1 (0.48) | TLR8MCHR1ALDH1A1HPGDCYP3A4 | |
| SCHEMBL16606236 | 0.76 | IRAK4 (0.61) | TLR8MCHR1IRAK4ALDH1A1HPGD | |
| SCHEMBL13865030 | 0.76 | TLR8 (0.50) | TLR8MCHR1IRAK4ALDH1A1HPGD | |
| SCHEMBL28770352 | 0.76 | ALDH1A1 (0.52) | TLR8MCHR1IRAK4ALDH1A1HPGD | |
| SCHEMBL5545202 | 0.73 | ALDH1A1 (0.62) | ALDH1A1HPGDCYP3A4TSHRHSD17B10 | |
| SCHEMBL29351158 | 0.73 | ALDH1A1 (0.62) | ALDH1A1HPGDCYP3A4TSHRHSD17B10 | |
| SCHEMBL2891381 | 0.71 | ALDH1A1 (0.59) | ALDH1A1HPGDCYP3A4TSHRHSD17B10 | |
| SCHEMBL29704534 | 0.71 | ALDH1A1 (0.59) | ALDH1A1HPGDCYP3A4TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487930-B1 | Benzo[C]phenanthridinium derivatives | NIPPON KAYAKU KK (JP) | 1999-03-24 | — | — | EP | disclosed |
| US-5747502-A | ANTITUMOR AGENTS, ANTIGROWTH AGENTS AND ANTICARCINOGENIC AGENTS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1998-05-05 | — | — | US | disclosed |
| EP-0487930-A1 | Process for preparing benzo[C]phenanthridinium derivatives, and novel compounds prepared by said process | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1992-06-03 | — | — | EP | disclosed |