Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NQO1 | P15559 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315056 | 0.88 | TLR8 (0.45) | ALDH1A1TDP1ADRA2BPTGS1IDO1 | |
| SCHEMBL5749415 | 0.86 | NQO1 (0.53) | ALDH1A1TDP1ADRA2BPTGS1IDO1 | |
| SCHEMBL5747064 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TDP1ADRA2BPTGS1IDO1 | |
| SCHEMBL8314710 | 0.79 | TLR8 (0.50) | ALDH1A1TDP1TLR8GAAMAPT | |
| SCHEMBL29101871 | 0.78 | ALDH1A1 (0.59) | ALDH1A1TDP1ADRA2BPTGS1IDO1 | |
| SCHEMBL29351158 | 0.78 | ALDH1A1 (0.62) | ALDH1A1TDP1GAAMAPTSMN1; SMN2 | |
| SCHEMBL5545202 | 0.78 | ALDH1A1 (0.62) | ALDH1A1TDP1GAAMAPTSMN1; SMN2 | |
| SCHEMBL10163672 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPTNQO1HPGDHSD17B10 | |
| SCHEMBL8501456 | 0.76 | KDM4E (0.52) | ALDH1A1PDE10AGAAMAPTNQO1 | |
| SCHEMBL11837586 | 0.76 | KDM4E (0.41) | ALDH1A1TDP1PDE10ATLR8GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9233911-B2 | Cu-mediated annulation for the production of 1-amino-2-naphthalenecarboxylic acid derivatives | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-01-12 | — | — | US | disclosed |
| US-20150011781-A1 | Cu-Mediated Annulation for the Production of 1-Amino-2-Naphthalenecarboxylic Acid Derivatives | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-01-08 | — | — | US | disclosed |
| US-8741917-B2 | Benzo [C] phenanthridines as antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-06-03 | — | — | US | disclosed |
| US-8741917-B2 | Benzo [C] phenanthridines as antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-06-03 | — | — | US | disclosed |
| US-8741917-B2 | Benzo [C] phenanthridines as antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-06-03 | — | — | US | disclosed |
| WO-2013105117-A1 | Cu-MEDIATED ANNULATION FOR THE PRODUCTION OF 1-AMINO-2-NAPHTHALENECARBOXYLIC ACID DERIVATIVES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-07-18 | — | — | WO | disclosed |
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUGTERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-01-26 | — | — | US | disclosed |
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUGTERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-01-26 | — | — | US | disclosed |
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUGTERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-01-26 | — | — | US | disclosed |
| EP-2387564-A1 | BENZO ÝC¨PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | Rutgers, The State University of New Jersey (US) | 2011-11-23 | — | — | EP | disclosed |
| US-8037884-B2 | Modular system for patient positioning during medical procedures | ALLEN MEDICAL SYSTEMS, INC. (US) | 2011-10-18 | — | — | US | disclosed |
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | disclosed |
| WO-2010083436-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-07-22 | — | — | WO | disclosed |
| WO-2010083436-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011781-A1 | Cu-Mediated Annulation for the Production of 1-Amino-2-Naphthalenecarboxylic Acid Derivatives | DDC, AOC2, AOC1 | ALDH1A1 459/4885TDP1 2523/4885ADRA2B 2672/4885 |
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | CCNT1, XPO4, XDH | ALDH1A1 3095/4885TDP1 1005/4885ADRA2B 3744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.