SCHEMBL8314717

SCHEMBL8314717

OC1COC(CBr)OCC1O

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL169073 0.76
SCHEMBL3655504 0.73
SCHEMBL19637957 0.73
SCHEMBL4996500 0.71
SCHEMBL12496179 0.71
SCHEMBL14178718 0.69 THRB (0.38) THRBLMNA
SCHEMBL18530039 0.69
SCHEMBL30598241 0.69
SCHEMBL18530025 0.69
SCHEMBL9181813 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0709387-B1 Bicycloaliphatic 2-methylene-1,3-dioxepanes IVOCLAR AG (LI) 1999-03-03 EP disclosed
US-5703249-A MONOMERS THAT CAN BE POLYMERIZED FOR USE AS COMPOSITES AND DENTAL MATERIALS IVOCLAR AG (LI) 1997-12-30 US disclosed
EP-0709387-A1 Bicycloaliphatic 2-methylene-1,3-dioxepanes IVOCLAR AG (LI) 1996-05-01 EP disclosed