Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | SLC26A4 | O43511 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | BCHE | P06276 | 5/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316127 | 0.90 | NPC1 (0.34) | NPC1ALDH1A1RAB9ALMNACASP3 | |
| SCHEMBL8309897 | 0.86 | NPC1 (0.32) | NPC1ALDH1A1RAB9ALMNACASP3 | |
| SCHEMBL8310437 | 0.84 | F2RL3 (0.35) | NPC1ALDH1A1RAB9ALMNACASP3 | |
| SCHEMBL8314737 | 0.83 | NPC1 (0.36) | NPC1ALDH1A1RAB9ALMNACASP3 | |
| SCHEMBL8314204 | 0.81 | KDM4E (0.39) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8314208 | 0.80 | F2RL3 (0.36) | NPC1ALDH1A1RAB9AHTTSLC26A4 | |
| SCHEMBL8310753 | 0.79 | ALDH1A1 (0.45) | NPC1ALDH1A1RAB9ALMNAHTT | |
| SCHEMBL8311891 | 0.79 | S1PR1 (0.39) | NPC1ALDH1A1RAB9ALMNACASP3 | |
| SCHEMBL8315798 | 0.78 | S1PR1 (0.38) | NPC1ALDH1A1RAB9ALMNACASP3 | |
| SCHEMBL8314569 | 0.77 | AR (0.36) | HTTSLC26A4MEN1KMT2AS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5296495-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |