SCHEMBL8314760

SCHEMBL8314760

Cc1cc(-c2c(S(C)(=O)=O)ccc(C(=O)C3C(=O)CC(C)N(C)C3=O)c2Cl)on1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CSF1R P07333 2/20 0.31
POLB P06746 2/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8311317 0.90 MEN1 (0.32) MEN1KMT2ACSF1R
SCHEMBL8314751 0.89 MEN1 (0.31) MAPTMEN1KMT2ACSF1R
SCHEMBL8314933 0.85 MEN1 (0.31) MAPTMEN1KMT2ACSF1R
SCHEMBL8309940 0.84 CSF1R (0.31) MAPTMEN1KMT2ACSF1RALDH1A1
SCHEMBL8138245 0.83 CSF1R (0.37) MAPTCSF1RPOLBALDH1A1
SCHEMBL8315388 0.82 CSF1R (0.31) CSF1RALDH1A1
SCHEMBL8137249 0.75 KDM4E (0.39) MAPTKMT2ACSF1RALDH1A1
SCHEMBL8135897 0.75 ALDH1A1 (0.48) MAPTMEN1KMT2ACSF1RALDH1A1
SCHEMBL8135835 0.73 PIK3CD (0.35) MAPTMEN1KMT2APOLBALDH1A1
SCHEMBL8135182 0.73 MEN1 (0.41) MAPTMEN1KMT2ACSF1RNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0949261-A1 SUBSTITUTED PIPERIDINEDIONE DERIVATIVES AND HERBICIDES NIPPON SODA CO., LTD. (JP) 1999-10-13 EP disclosed