Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315190 | 0.90 | RECQL (0.33) | EGFRRECQLAKR1B1 | |
| SCHEMBL8313489 | 0.89 | MAPT (0.34) | EGFRRECQLAKR1B1HPRT1 | |
| SCHEMBL8313498 | 0.85 | RECQL (0.32) | EGFRRECQLAKR1B1 | |
| SCHEMBL8312387 | 0.83 | ALDH1A1 (0.37) | AKR1B1CTSL | |
| SCHEMBL6269281 | 0.81 | — | — | |
| SCHEMBL6267682 | 0.80 | — | — | |
| SCHEMBL8121742 | 0.79 | CTSL (0.37) | EGFRAKR1B1CTSL | |
| SCHEMBL8316418 | 0.79 | MAPT (0.37) | RECQLAKR1B1 | |
| SCHEMBL8315380 | 0.79 | — | — | |
| SCHEMBL6270429 | 0.77 | AKR1B1 (0.40) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632033-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| US-5646308-A | POTASSIUM CHANNEL ACTIVATORS USED AS ANTIASTHMATICS, ANTIEPILEPTICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-07-08 | — | — | US | disclosed |
| EP-0632033-A1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-01-04 | — | — | EP | disclosed |