SCHEMBL8314928

SCHEMBL8314928

Nc1ccc(OC2CCC(Oc3ccc(N)cc3)CC2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.50
TSHR P16473 2/20 0.50
ALDH1A1 P00352 2/20 0.50
CYP3A4 P08684 2/20 0.50
PARP10 Q53GL7 1/20 0.48
MAPK1 P28482 1/20 0.46
HRH1 P35367 2/20 0.45
PTPN1 P18031 1/20 0.43
NFE2L2 Q16236 1/20 0.42
MAOA P21397 2/20 0.42
MAPT P10636 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
FURIN P09958 2/20 0.41
MAP4K4 O95819 1/20 0.41
TEAD4 Q15561 1/20 0.41
MAOB P27338 1/20 0.41
HRH3 Q9Y5N1 1/20 0.40
SLC6A4 P31645 2/20 0.39
SLC6A2 P23975 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6903727 1.00 TDP1 (0.50) TDP1TSHRALDH1A1CYP3A4PARP10
SCHEMBL747626 0.90 PARP10 (0.55) TDP1TSHRALDH1A1CYP3A4PARP10
SCHEMBL10187265 0.90 PARP10 (0.60) TDP1TSHRALDH1A1CYP3A4PARP10
SCHEMBL13724423 0.89 PARP10 (0.46) TDP1TSHRALDH1A1CYP3A4PARP10
SCHEMBL12056318 0.89 MCHR1 (0.44) TDP1TSHRALDH1A1CYP3A4PARP10
SCHEMBL623629 0.88 PARP10 (0.53) TDP1TSHRALDH1A1CYP3A4PARP10
SCHEMBL26012610 0.88 PARP10 (0.53) TDP1TSHRALDH1A1CYP3A4PARP10
SCHEMBL2957422 0.84 PARP10 (0.42) TDP1TSHRALDH1A1CYP3A4PARP10
SCHEMBL1208630 0.84 DHFR (0.46) TDP1TSHRALDH1A1CYP3A4PARP10
SCHEMBL6121373 0.84 HRH1 (0.68) PARP10HRH1HRH3SLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113930248-B Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element 奇美实业股份有限公司 2025-02-11 CN disclosed
CN-113930247-B Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element 奇美实业股份有限公司 2025-02-11 CN disclosed
CN-113773858-B Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display assembly 奇美实业股份有限公司 2024-10-29 CN disclosed
CN-118011690-A Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display assembly 奇美实业股份有限公司 2024-05-10 CN disclosed
CN-110499164-B Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element 奇美实业股份有限公司 2023-12-05 CN disclosed
CN-112852446-B Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element 奇美实业股份有限公司 2023-11-17 CN disclosed
CN-115595159-A Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display assembly 奇美实业股份有限公司(TW) 2023-01-13 CN disclosed
CN-109085722-B Method for manufacturing liquid crystal alignment film and liquid crystal display element 奇美实业股份有限公司 2022-05-10 CN disclosed
EP-0597102-B1 NOVEL BISHETEROCYCLIC DERIVATIVE OR SALT THEREOF AND HYPOGLYCEMIC COMPOSITION YAMANOUCHI PHARMA CO LTD (JP) 1999-01-07 EP disclosed
US-5508296-A HYPOGLYCEMIC AGENTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1996-04-16 US disclosed
EP-0597102-A1 NOVEL BISHETEROCYCLIC DERIVATIVE OR SALT THEREOF YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1994-05-18 EP disclosed