Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.69 |
| ▸ | PPARA | Q07869 | 16/20 | 0.69 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6218072 | 0.84 | PPARG (0.57) | PPARGPPARA | |
| SCHEMBL13603776 | 0.83 | PPARG (0.69) | PPARGPPARAPTPN7MEN1MAPT | |
| SCHEMBL30559867 | 0.83 | PPARG (0.77) | PPARGPPARAPTPN7MEN1MAPT | |
| SCHEMBL8935921 | 0.83 | PPARG (0.77) | PPARGPPARAPTPN7MEN1MAPT | |
| SCHEMBL8935913 | 0.83 | PPARG (0.77) | PPARGPPARAPTPN7MEN1MAPT | |
| SCHEMBL3046273 | 0.82 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL8564894 | 0.80 | PPARG (0.64) | PPARGPPARAPTPN7MEN1MAPT | |
| SCHEMBL8559718 | 0.80 | PPARG (0.64) | PPARGPPARAPTPN7MEN1MAPT | |
| SCHEMBL8560729 | 0.80 | PPARG (0.64) | PPARGPPARAPTPN7MEN1MAPT | |
| SCHEMBL10599723 | 0.78 | PPARG (0.70) | PPARGPPARAPTPN7TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629626-B1 | Cyclopropyl-substituted spiro-photochromic compounds | TOKUYAMA CORP (JP) | 1999-10-27 | — | — | EP | disclosed |
| US-5708063-A | REVERSABLE COLOR COMPOUNDS | TOKUYAMA CORPORATION (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0629626-A2 | Cyclopropyl-substituted spiro-photochromic compounds | TOKUYAMA CORPORATION (JP) | 1994-12-21 | — | — | EP | disclosed |