Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 7/20 | 0.49 |
| ▸ | PPARA | Q07869 | 7/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | OGG1 | O15527 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935882 | 0.84 | PPARG (0.67) | KDM4EALDH1A1HPGDTDP1PPARG | |
| SCHEMBL10389731 | 0.84 | KDM4E (0.55) | KDM4EALDH1A1HPGDTDP1PPARG | |
| SCHEMBL8821208 | 0.84 | PPARG (0.67) | KDM4EALDH1A1HPGDTDP1PPARG | |
| SCHEMBL8564033 | 0.81 | GRIK1 (0.48) | KDM4EALDH1A1HPGDTDP1PPARG | |
| SCHEMBL8564030 | 0.81 | GRIK1 (0.48) | KDM4EALDH1A1HPGDTDP1PPARG | |
| SCHEMBL10389987 | 0.80 | KDM4E (0.47) | KDM4EALDH1A1HPGDTDP1PPARG | |
| SCHEMBL27478671 | 0.80 | PPARG (0.51) | KDM4EALDH1A1HPGDTDP1PPARG | |
| SCHEMBL28840585 | 0.79 | KDM4E (0.51) | KDM4EALDH1A1HPGDTDP1PPARG | |
| SCHEMBL10389806 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1HPGDTDP1PPARG | |
| SCHEMBL9345655 | 0.78 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDTDP1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629626-B1 | Cyclopropyl-substituted spiro-photochromic compounds | TOKUYAMA CORP (JP) | 1999-10-27 | — | — | EP | disclosed |
| US-5708063-A | REVERSABLE COLOR COMPOUNDS | TOKUYAMA CORPORATION (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0629626-A2 | Cyclopropyl-substituted spiro-photochromic compounds | TOKUYAMA CORPORATION (JP) | 1994-12-21 | — | — | EP | disclosed |