Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.67 |
| ▸ | PPARA | Q07869 | 9/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8821208 | 1.00 | PPARG (0.67) | PPARGPPARAALDH1A1KDM4EHPGD | |
| SCHEMBL27478671 | 0.85 | PPARG (0.51) | PPARGPPARAALDH1A1KDM4EHPGD | |
| SCHEMBL8315327 | 0.84 | KDM4E (0.51) | PPARGPPARAALDH1A1KDM4EHPGD | |
| SCHEMBL10389731 | 0.84 | KDM4E (0.55) | PPARGPPARAALDH1A1KDM4EHPGD | |
| SCHEMBL7418048 | 0.84 | PPARG (0.49) | PPARGPPARAALDH1A1KDM4EHPGD | |
| SCHEMBL10722586 | 0.84 | PPARG (0.49) | PPARGPPARAALDH1A1KDM4EHPGD | |
| SCHEMBL8065096 | 0.83 | KDM4E (0.49) | PPARGPPARAALDH1A1KDM4EHPGD | |
| SCHEMBL11068097 | 0.83 | PPARA (0.51) | PPARGPPARAHSD17B10GAASLC6A2 | |
| SCHEMBL3144299 | 0.83 | PPARA (0.50) | PPARGPPARATSHRSMN1; SMN2 | |
| SCHEMBL11866215 | 0.82 | OGG1 (0.52) | PPARGPPARAALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |