Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3637064 | 0.82 | ACP3 (0.49) | ACP3CYP19A1ACHELMNAALOX12 | |
| SCHEMBL3910832 | 0.80 | TAAR1 (0.64) | ACP3CYP19A1ACHEAOC3TAAR1 | |
| SCHEMBL8321990 | 0.80 | ACP3 (0.47) | ACP3CYP19A1ACHELMNAALOX12 | |
| SCHEMBL1666064 | 0.80 | HTR2A (0.52) | ALDH1A1TAAR1TSHR | |
| SCHEMBL8683334 | 0.78 | ACP3 (0.46) | ACP3CYP19A1ACHELMNAALOX12 | |
| SCHEMBL6546957 | 0.78 | CYP19A1 (0.51) | ACP3CYP19A1ACHELMNAALOX12 | |
| SCHEMBL7787303 | 0.78 | ACP3 (0.44) | ACP3ACHELMNAHTTALDH1A1 | |
| SCHEMBL27692682 | 0.78 | ACHE (0.44) | ACP3CYP19A1ACHEMAPTHTT | |
| SCHEMBL6703971 | 0.77 | HRH1 (0.67) | ACP3CYP19A1LMNAALOX12MAPT | |
| SCHEMBL27466804 | 0.77 | CYP19A1 (0.50) | ACP3CYP19A1LMNAALOX12MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929534-A1 | TRYCYCLIC COMPOUNDS AS PROSTAGLANDIN I2 RECEPTOR AGONISTS | Takeda Pharmaceutical Company Limited (JP) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998013356-A1 | TRYCYCLIC COMPOUNDS AS PROSTAGLANDIN I2 RECEPTOR AGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-04-02 | — | — | WO | disclosed |