Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317297 | 0.89 | HRH1 (0.39) | CYP2J2SLC6A4SLC6A2HRH1KCNH2 | |
| SCHEMBL8315487 | 0.87 | CYP2J2 (0.39) | PAX8CYP2J2SLC6A4SLC6A2HRH1 | |
| SCHEMBL8317157 | 0.85 | CYP2J2 (0.45) | PAX8CYP2J2HRH1KCNH2 | |
| SCHEMBL8313333 | 0.85 | HRH1 (0.43) | PAX8CYP2J2SLC6A4SLC6A2HRH1 | |
| SCHEMBL8314774 | 0.84 | CYP2J2 (0.47) | PAX8CYP2J2HRH1KCNH2 | |
| SCHEMBL8316037 | 0.81 | HRH1 (0.46) | CYP2J2SLC6A4SLC6A2HRH1KCNH2 | |
| SCHEMBL8523260 | 0.81 | HRH1 (0.37) | CYP2J2SLC6A4SLC6A2HRH1KCNH2 | |
| SCHEMBL8317429 | 0.81 | HRH1 (0.39) | CYP2J2SLC6A4SLC6A2HRH1KCNH2 | |
| SCHEMBL8312317 | 0.80 | HRH1 (0.48) | CYP2J2SLC6A4SLC6A2HRH1KCNH2 | |
| SCHEMBL8315211 | 0.80 | HRH1 (0.46) | CYP2J2SLC6A4SLC6A2HRH1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |