Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.32 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312063 | 0.91 | ALOX5 (0.34) | ALOX5MAOBABCB1CYP26A1CYP26B1 | |
| SCHEMBL8314939 | 0.88 | MAOB (0.34) | ALOX5MAOBABCB1CYP26A1CYP26B1 | |
| SCHEMBL8315203 | 0.84 | PDE9A (0.31) | ALOX5MAOB | |
| SCHEMBL8314291 | 0.84 | KMT2A (0.43) | ALOX5MAOBCYP26A1CYP26B1HTT | |
| SCHEMBL8314208 | 0.83 | F2RL3 (0.36) | MAOBCYP19A1F2RL3HTTHDAC6 | |
| SCHEMBL8316475 | 0.83 | CYP26A1 (0.33) | MAOBCYP26A1CYP26B1CYP19A1 | |
| SCHEMBL5800338 | 0.82 | CYP26A1 (0.37) | CYP26A1CYP26B1CYP19A1 | |
| SCHEMBL6598943 | 0.79 | CYP2C8 (0.37) | ALOX5CYP26A1CYP26B1CYP19A1 | |
| SCHEMBL8314759 | 0.76 | CYP26A1 (0.34) | MAOBCYP26A1CYP26B1CYP19A1HTT | |
| SCHEMBL8310276 | 0.76 | CHRM2 (0.41) | ALOX5CYP26A1CYP26B1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5296495-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |