Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315448 | 0.91 | ALOX5 (0.34) | ALOX5MAOBCYP26A1CYP26B1HDAC6 | |
| SCHEMBL8314939 | 0.88 | MAOB (0.34) | ALOX5MAOBCYP26A1CYP26B1HDAC6 | |
| SCHEMBL8315203 | 0.84 | PDE9A (0.31) | ALOX5MAOB | |
| SCHEMBL8314291 | 0.84 | KMT2A (0.43) | ALOX5MAOBCYP26A1CYP26B1MAOA | |
| SCHEMBL8310276 | 0.82 | CHRM2 (0.41) | ALOX5CYP26A1CYP26B1PTGESCYP19A1 | |
| SCHEMBL8314759 | 0.82 | CYP26A1 (0.34) | MAOBCYP26A1CYP26B1HDAC6MAOA | |
| SCHEMBL6599311 | 0.77 | ALOX5 (0.48) | ALOX5MAOBCYP26A1CYP26B1MAOA | |
| SCHEMBL5800338 | 0.76 | CYP26A1 (0.37) | CYP26A1CYP26B1CYP19A1MEN1KMT2A | |
| SCHEMBL8316064 | 0.76 | FFAR1 (0.42) | CYP26A1CYP26B1MEN1KMT2AFFAR1 | |
| SCHEMBL8314208 | 0.75 | F2RL3 (0.36) | MAOBHDAC6CYP19A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5296495-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |