Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 4/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948697 | 0.87 | GRM2 (0.50) | GRM2SIGMAR1 | |
| SCHEMBL8316389 | 0.86 | SIGMAR1 (0.41) | GRM2SIGMAR1MAPT | |
| SCHEMBL8948494 | 0.82 | GRM2 (0.53) | GRM2SIGMAR1 | |
| SCHEMBL8311049 | 0.82 | GRM2 (0.53) | GRM2SIGMAR1 | |
| SCHEMBL8948618 | 0.82 | GRM2 (0.53) | GRM2SIGMAR1 | |
| SCHEMBL8948743 | 0.82 | GRM2 (0.50) | GRM2SIGMAR1 | |
| SCHEMBL8313964 | 0.81 | GRM2 (0.54) | GRM2SIGMAR1 | |
| SCHEMBL8458455 | 0.80 | GRM2 (0.48) | GRM2SIGMAR1 | |
| SCHEMBL8948726 | 0.79 | GRM2 (0.52) | GRM2SIGMAR1 | |
| SCHEMBL8948849 | 0.79 | GRM2 (0.52) | GRM2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623615-B1 | Substituted 1-phenyl-oxazolidin-2-one derivatives, their preparation and their use as adhesion-receptor antagonists | MERCK PATENT GMBH (DE) | 1999-06-30 | — | — | EP | disclosed |
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |
| EP-0623615-A1 | Adhesion-receptor antagonists | MERCK PATENT GmbH (DE) | 1994-11-09 | — | — | EP | disclosed |