Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.61 |
| ▸ | GPR35 | Q9HC97 | 9/20 | 0.55 |
| ▸ | PON1 | P27169 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14405907 | 0.88 | MAOB (0.60) | MAOBGPR35MAOAKDM4EALDH1A1 | |
| SCHEMBL29628919 | 0.84 | GPR35 (0.76) | MAOBGPR35MAOAKDM4EALDH1A1 | |
| SCHEMBL980268 | 0.84 | GPR35 (0.76) | MAOBGPR35MAOAKDM4EALDH1A1 | |
| SCHEMBL24450681 | 0.82 | MAOB (0.66) | MAOBGPR35MAOAKDM4EALDH1A1 | |
| SCHEMBL11510368 | 0.79 | MAOA (0.73) | MAOBGPR35MAOAKDM4EALDH1A1 | |
| SCHEMBL11070463 | 0.79 | MEN1 (0.71) | MAOBKDM4EALDH1A1GLAGAA | |
| SCHEMBL2791740 | 0.78 | AKR1B1 (0.61) | GPR35PON1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL18752500 | 0.78 | KDM4E (0.63) | MAOBGPR35MAOAKDM4EALDH1A1 | |
| SCHEMBL10650556 | 0.77 | CA12 (0.56) | MAOBMAOAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL6490749 | 0.76 | MAOB (0.72) | MAOBGPR35MAOAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0093376-B2 | 1-Sulfo-2-azetidinone derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| EP-0093376-B1 | 1-SULFO-2-AZETIDINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-03-21 | — | — | EP | disclosed |
| US-4782147-A | ANTIBIOTIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-11-01 | — | — | US | disclosed |
| EP-0076463-B1 | BETA-LACTAM COMPOUND AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1988-08-17 | — | — | EP | disclosed |
| US-4694001-A | ANTIBIOTICS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1987-09-15 | — | — | US | disclosed |
| US-4468394-A | Cephalosporin compounds | EISAI CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4415567-A | A 7B-CHROMONE-3-CARBOXAMIDO-2-/4-HYDROXY PHENYL/ACETAMIDO-2-CEPHEM DERIVATIVE | EISAI CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |
| EP-0093376-A2 | 1-Sulfo-2-azetidinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1983-11-09 | — | — | EP | disclosed |
| EP-0076463-A2 | Beta-lactam compound and a pharmaceutical composition containing the same | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1983-04-13 | — | — | EP | disclosed |
| EP-0062328-A2 | Novel penicillin and cephalosporin compounds, a process for preparing the same and antibacterial composition containing the novel compounds | Eisai Co., Ltd. (JP) | 1982-10-13 | — | — | EP | disclosed |
| US-4344944-A | 7-α-methoxycephalosporin derivatives, and antibacterial drugs onctaining the same | EISAI CO., LTD. (JP) | 1982-08-17 | — | — | US | disclosed |
| EP-0054578-A1 | N-(substituted chromone-3-carbonyl)-phenylglycine derivatives | Eisai Co., Ltd. (JP) | 1982-06-30 | — | — | EP | disclosed |
| US-4331606-A | BACTERICIDES, CEPHALOSPORIN INTERMEDIATES | EISAI CO., LTD. (JP) | 1982-05-25 | — | — | US | disclosed |
| US-4285941-A | ANTIBIOTICS | EISAI CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |
| US-4285940-A | ANTIBIOTICS | EISAI CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |
| US-4285939-A | ANTIBIOTICS | EISAI CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |