Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 11/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10517674 | 0.84 | MAOB (0.57) | ALOX12ALOX15MAOBMAOAADORA2B | |
| SCHEMBL8628824 | 0.83 | ALOX12 (0.50) | ALOX12ALOX15MAOBMAOAADORA2B | |
| Hydrochloric Acid SCHEMBL10516530 | 0.83 | MAOB (0.56) | ALOX12ALOX15MAOBMAOAADORA2B | |
| SCHEMBL8628828 | 0.83 | ALOX12 (0.50) | ALOX12ALOX15MAOBMAOAADORA2B | |
| SCHEMBL11370039 | 0.80 | KDM4E (0.56) | MAOBMAOAMIFXDH | |
| SCHEMBL10650560 | 0.76 | KDM4E (0.48) | ALOX12ALOX15MAOBPTPN1 | |
| SCHEMBL9029206 | 0.74 | MAOB (0.72) | MAOBMAOAADORA2B | |
| SCHEMBL16446088 | 0.73 | ALOX12 (0.54) | ALOX12ALOX15MAOBMAOAPTPN1 | |
| SCHEMBL10961044 | 0.71 | KMT2A (0.47) | MAOB | |
| SCHEMBL11356469 | 0.71 | NPC1 (0.61) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0093376-B2 | 1-Sulfo-2-azetidinone derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| EP-0093376-B1 | 1-SULFO-2-AZETIDINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-03-21 | — | — | EP | disclosed |
| EP-0303286-A1 | 2-Oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines | E.R. Squibb & Sons, Inc. (US) | 1989-02-15 | — | — | EP | disclosed |
| US-4782147-A | ANTIBIOTIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-11-01 | — | — | US | disclosed |
| US-4777252-A | 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines | E. R. SQUIBB & SONS, INC. (US) | 1988-10-11 | — | — | US | disclosed |
| EP-0076463-B1 | BETA-LACTAM COMPOUND AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1988-08-17 | — | — | EP | disclosed |
| US-4694001-A | ANTIBIOTICS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1987-09-15 | — | — | US | disclosed |
| US-4546176-A | 7-Carboxymethoxyphenylacetamido-3-cephem derivatives and antibacterial preparations containing the same | EISAI CO., LTD. (JP) | 1985-10-08 | — | — | US | disclosed |
| US-4448775-A | 3-Carbamoyloxymethylcephem derivatives, and antibacterial drugs containing same | EISAI CO., LTD. (JP) | 1984-05-15 | — | — | US | disclosed |
| US-4415567-A | A 7B-CHROMONE-3-CARBOXAMIDO-2-/4-HYDROXY PHENYL/ACETAMIDO-2-CEPHEM DERIVATIVE | EISAI CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |
| EP-0093376-A2 | 1-Sulfo-2-azetidinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1983-11-09 | — | — | EP | disclosed |
| EP-0076463-A2 | Beta-lactam compound and a pharmaceutical composition containing the same | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1983-04-13 | — | — | EP | disclosed |
| EP-0075928-A2 | 3-Carbamoyloxymethylcephem derivatives, processes for the preparation thereof, and antibacterial drugs containg same | Eisai Co., Ltd. (JP) | 1983-04-06 | — | — | EP | disclosed |
| US-4344944-A | 7-α-methoxycephalosporin derivatives, and antibacterial drugs onctaining the same | EISAI CO., LTD. (JP) | 1982-08-17 | — | — | US | disclosed |
| EP-0054578-A1 | N-(substituted chromone-3-carbonyl)-phenylglycine derivatives | Eisai Co., Ltd. (JP) | 1982-06-30 | — | — | EP | disclosed |
| US-4331606-A | BACTERICIDES, CEPHALOSPORIN INTERMEDIATES | EISAI CO., LTD. (JP) | 1982-05-25 | — | — | US | disclosed |
| US-4285941-A | ANTIBIOTICS | EISAI CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |
| US-4285940-A | ANTIBIOTICS | EISAI CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |
| US-4285939-A | ANTIBIOTICS | EISAI CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |