Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 10/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10517674 | 0.84 | MAOB (0.57) | ALOX12ALOX15MAOBMAOAADORA2B | |
| SCHEMBL8315659 | 0.83 | ALOX12 (0.50) | ALOX12ALOX15MAOBMAOAADORA2B | |
| Hydrochloric Acid SCHEMBL10516530 | 0.83 | MAOB (0.56) | ALOX12ALOX15MAOBMAOAADORA2B | |
| SCHEMBL8628824 | 0.83 | ALOX12 (0.50) | ALOX12ALOX15MAOBMAOAADORA2B | |
| SCHEMBL17855977 | 0.77 | NPC1 (0.51) | MAOBMAOANPC1MAPTRAB9A | |
| SCHEMBL30643087 | 0.76 | MAOB (0.64) | MAOBMAOANPC1MAPT | |
| SCHEMBL4974849 | 0.74 | MAOB (0.72) | MAOBMAOAADORA2BNPC1MAPT | |
| SCHEMBL30643084 | 0.74 | MAOB (0.72) | MAOBMAOAADORA2BNPC1MAPT | |
| SCHEMBL16446088 | 0.73 | ALOX12 (0.54) | ALOX12ALOX15MAOBMAOANPC1 | |
| SCHEMBL8122069 | 0.73 | MAOB (0.48) | ALOX12ALOX15MAOBMAOAADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801242-A | Process for making quinolonyl lactam antimicrobials and novel intermediate compounds | THE PROCTER & GAMBLE COMPANY (US) | 1998-09-01 | — | — | US | disclosed |
| US-5703231-A | Process for making antimicrobial compounds | THE PROCTER & GAMBLE COMPANY (US) | 1997-12-30 | — | — | US | disclosed |
| CN-1158120-A | Process for the preparation of antimicrobial compounds | PROCTER & GAMBLE (US) | 1997-08-27 | — | — | CN | disclosed |